Shanghai Zhicheng successfully developed online optical density detection shaker
In the field of bio-fermentation in China, the backward experimental methods for understanding the growth characteristics of microbial strains will be completely changed by manual sampling. After years of research, researchers of Shanghai Zhicheng Analytical Instrument Manufacturing Co., Ltd. have successfully developed a new ZWYF-290B online optical density detection shaker using non-contact technology for online real-time detection of OD values ​​of microbial strains. It is understood that the advent of this patented product has changed the flaws in China's bio-fermentation field without such domestic equipment.
As we all know, the rapid development of research and application of bio-fermentation technology in China has made China into the ranks of fermenting countries in the world of bio-engineering. However, compared with developed countries, China's scientific research level and scientific research achievements in this field still have a large gap. The backwardness of experimental equipment is one of the important reasons. At present, the cultivation and research of microbial strains in the field of bioengineering fermentation in China also follows the traditional experimental method of understanding the growth characteristics of microbial strains by manual sampling. This manual operation method is not only time-consuming and labor-intensive, but also has low accuracy and poor repeatability, and its research efficiency is still very low. This situation has become an important bottleneck for the cultivation and screening of microbial strains in the field of bio-fermentation engineering in China. The experimental personnel in the field of biological fermentation are eager to have domestically produced automated testing equipment available soon, which will free them from the cumbersome and cumbersome experimental operations and realize our long-cherished wish to move from a fermenting country to a fermenting power.
ZWYF-290B online optical density detection shaker is a new type of constant temperature shaker that uses non-contact detection technology to perform on-line real-time detection of optical density (OD) values ​​of microbial cell concentration. The product is equipped with a non-invasive multi-channel photometric detector on a superimposed true color touch screen shaker. In real time, the optical density of cells in the microbial fermentation broth is measured in real time, and the concentration or particle size change of microbial growth is tracked online for bioengineering. Biomedical and biopharmaceuticals provide a basic new bioreactor. The product uses a laser source with a wavelength of 600/660 nm and uses a 250 mL special cone-shaped triangular flask as a bio-fermentation shake flask to meet the requirements of general microbial fermentation process detection and cell growth rate online analysis. The new product has strong anti-interference noise and can obtain real microbial cell growth curves in a vibration environment of 250 rpm. The equipment is available in 4, 8, 12 and 16 channels, suitable for orthogonal test, uniform experiment and DoE design experiment, so as to efficiently achieve strain screening, medium optimization, process optimization and kinetic analysis. In addition, the wireless data acquisition and transmission functions configured by the product create conditions for further multi-machine networking and high-throughput big data bio-reaction and analysis.
The product is suitable for strain screening, medium optimization, fermentation process optimization and other research, which can significantly improve process optimization and screening efficiency. It can also be widely used in the cultivation and fermentation of microbial cells, animal cells and plant cells, and has a good application prospect in the field of biotechnology, food development, bio-agriculture, environmental management and other fields for strain screening and process development. According to research needs, the product can also be used to replace laser wavelengths and be used for the detection of active substances such as enzymes and proteins.
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