Basic Info
 

Product Description

Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Quick Details:
Product Name: Follistatin 315
Specification: 1mg/vial
Purity (by HPLC) :≥98.0%
Appearance : White powder
Usuage: Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.

Description:
 
Follistatin is a secreted glycoprotein that was first identified as a follicle­stimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an N­terminal atypical TGF binding domain, three Follistatin domains that contain EGF ­like and kazal­like motifs, and a highly acidic C­terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.
 
It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.

Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene.Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

 

Follistatin 315 (FST 315 ) Function: 

Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).

Follistatin 315 (FST 315 ) Storage Buffer:

PBS, 0.09% Sodium Azide

Follistatin 315 (FST 315 ) Storage Instruction:

Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. This product may contain precipitation. Recommend microcentrifugation before use.

 

 

 

Basic Info
 

Product Description

Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Hot Sale Polypeptide Hormone Follistatin315 1mg/Vial for Muscle Building
Quick Details:
Product Name: Follistatin 315
Specification: 1mg/vial
Purity (by HPLC) :≥98.0%
Appearance : White powder
Usuage: Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.

Description:
 
Follistatin is a secreted glycoprotein that was first identified as a follicle­stimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an N­terminal atypical TGF binding domain, three Follistatin domains that contain EGF ­like and kazal­like motifs, and a highly acidic C­terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.
 
It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.

Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene.Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

 

Follistatin 315 (FST 315 ) Function: 

Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).

Follistatin 315 (FST 315 ) Storage Buffer:

PBS, 0.09% Sodium Azide

Follistatin 315 (FST 315 ) Storage Instruction:

Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. This product may contain precipitation. Recommend microcentrifugation before use.

 

 

 

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